Beilstein J. Org. Chem.2022,18, 1672–1695, doi:10.3762/bjoc.18.179
aimed at overviewing the current state-of-art and perspectives of oxidative organocatalysis by redox-activemolecules with the emphasis on challenging chemo-, regio- and stereoselective CH-functionalization processes. The catalytic systems based on N-oxyl radicals, amines, thiols, oxaziridines, ketone
/peroxide, quinones, and iodine(I/III) compounds are the most developed catalyst types which are covered here.
Keywords: CH-functionalization; free radicals; hypervalent iodine; N-oxyl radicals; redox-activemolecules; Introduction
Organocatalysis can be defined as catalysis by small organic molecules
redox-neutral asymmetric organocatalysis, whereas organocatalysis by redox-activemolecules stays in the shadows. For example, redox-active organic molecules are almost not mentioned in some recent overviews of compound types used in organocatalysis [3][12][13], except for photoredox catalysts [12][13
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Graphical Abstract
Scheme 1:
Organocatalysis classification used in the present perspective.